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The BIOFIRE System and Your Immune System The BIOFIRE System provides syndromic infectious disease testing, empowering healthcare providers to select the most appropriate test, the first time. Patients benefit from quicker diagnosis and more targeted treatments. Clinicians benefit from improved stewardship for antibiotics. Labs improve efficiency and cost savings. The BioFire FilmArray Pneumonia plus panel (PN panel) analyzes native sputum endotracheal aspirate, and bronchoalveolar lavage specimens (including mini-BAL) for 33 pathogens that are clinically relevant and antimicrobial resistance genes, with semiquantitative results in about an hour. Respiratory The burning of biomass, such as plants, wood and other organic materials produces gaseous pollutants and fine particles that negatively affect the respiratory system. Moreover, the environmental problems caused by forest fires like droughts, could be exacerbated by climate change, increasing their negative impact on the health of humans. In the United States, wildfire smoke has been associated with hospitalizations for respiratory illnesses, including asthma, COPD and lung cancer. Furthermore, this type of air pollution is an underlying risk factor for cardiovascular diseases and is a significant contributor to the burden of illness among the most vulnerable populations, including people with lower socioeconomic status (SES). During the COVID-19 epidemic, many communities were exposed to unhealthy levels of air pollution resulting from wildfires. However the response of public health officials to this environmental issue has been sporadic and mostly focused on communicating about symptom management. This gap in knowledge is concerning given the evidence of potential health hazards from the continued exposure to smoke and other causes of poor air quality. Researchers are now evaluating the best way to safeguard public's health during any future events of this nature. bio-ethanol fire is funding research on this critical public health problem through the BLUE CORAL study and its successor, FIRE CORAL. First time that a prospective study is conducted, it will examine the long-term effects of exposure to smoke from wildfires or other sources. FIRE CORAL is looking for adult participants who have been hospitalized for the index episode of COVID-19 who speak English or Spanish and are not pregnant. The Fire Coral protocol includes a variety of assessments in person that objectively measure pulmonary function testing, lung imaging and functional assessment. Smoke and other particles can trigger or worsen chronic respiratory conditions such as emphysema, COPD and pneumonia. A variety of steps can be taken to avoid or lessen the negative health effects from short-term exposures to smoke, which includes avoidance of outdoor activities whenever possible and wearing the EPA's “N95” mask, which is designed to capture fine particles. Smoking can cause irritation of the throat and eyes, and cause the nose to run. To reduce the symptoms, drink lots of water and take medications that reduce inflammation, such corticosteroids. Bloodstream Bloodstream is the first line of defense against germs that invade your system. Special cells called dendritic cells are like your fire department's call center; they collect the antigens (molecules that trigger an immune response) from germs that are invading your body and then release proteins that trigger other white blood cells to come to fight them. The total number of white blood cells, differentials, and band cells grew after firefighters' fire-fighting duties, compared to levels after strenuous exercise without fire-fighting. Skin As the wildfires in California produced smoke and smoke into the air over the course of fall and winter dermatologists were concerned how that might affect the skin of those who were exposed to it. Maria Wei is a graduate student from University of California, Irvine. She investigates how the extreme pollution from wildfires affects the skin. Her research was published on April 22, 2012 in Scientific Reports. Wei's research has shown that the temperature of the skin changes based on how long the body is exposed to flames. It can take as long as two hours for the skin of someone to reach their “flash point”—the point where it begins to burn and then turn into ash. It's important not to stay close to a fire or campfire and wear protective clothing if you're out on a hot or humid day. Forest fires will continue to occur, despite the measures taken to stop wildfire pollution. Wei is predicting that the number of people suffering the effects of wildfires will grow as climate change causes more and more forests to burn. This means that more people will need to wear hats and long sleeves and also thick moisturizers. Wildfire air pollution can also exacerbate atopic skin dermatitis, which is a condition that causes itchy skin in many people. She suggests that this is because smoke particles can block pores, which makes the condition worse. Atopic dermatitis can cause people to be more sensitive towards UV light. This can be exacerbated by smoke from wildfires. This makes people more likely to visit tanning salons, and could cause people to tan less protection than they ought to. While a fire and ice facial may reduce the effects of atopic dermatitis it's not recommended for anyone who has an open wound or rash on their face. Patients with active acne should avoid it and if you're breastfeeding or pregnant, it is recommended to stay clear of this treatment altogether. The IS Clinical Fire & Ice Facial is offered at Novuskin Las Vegas' premier membership MedSpa is a results-driven, intensive facial that bridges a mild facelift and a peel, but without the need for time off. It's designed to resurface the skin, alleviate rosacea symptoms, decrease acne scarring, reduce fine lines, and encourage the renewal of cells. It's an incredible treatment to give yourself radiant skin. Infections The human body is made up of a complex set of organs and tissues that work together in order to protect us against infection. Infections are caused by microscopic organisms such as bacteria, viruses, parasites and fungus that infiltrate healthy cells and cause them to multiply beyond control. Your immune system can react by displaying signs of illness. The symptoms could range from a stuffy or runny nose to stomach ache and can include a fever high or swollen glands. You may also experience a skin rash. The type of infection and its location can affect the severity of your symptoms. Infections can spread in a variety of ways, but the most common are spread from person to via droplets that remain in the air after sneezing or coughing. Bacterial diseases such as tuberculosis, strep throat, meningococcal disease, and Legionnaires' disease spread through this method, along with certain viral infections such as the common cold and influenza. Certain bacterial infections, such as skin infections or sexually transmitted diseases (STIs) such as Chlamydia and gonorrhea can be transmitted through direct contact with affected mucous surfaces or tissues, or indirectly through contaminated surfaces. Certain bacterial infections are carried by bugs like mosquitoes, ticks or fleas and can be spread by bites from these bugs you. Viruses, parasites, and other microorganisms are small enough to enter the bloodstream and cause infection to your cells. This can lead to serious diseases such as the common cold or AIDS. Fungi are responsible for a myriad of skin conditions such as ringworm, athlete's foot. Some infect the lungs or nervous system, such as the rabies virus. The BioFire Panel employs our revolutionary FilmArray Technology to test the sputum and bronchoalveolar fluid samples to determine a comprehensive list of pathogens that are involved in upper respiratory infections. The kit comes with a reagent pouch that stores all the chemistry needed to perform reverse transcription PCR, multiplex nested testing and detection using a single machine. It's a simple-to-use tool to assist clinicians in identifying syndromic patterns and treat patients suffering from different respiratory symptoms. The test has been granted an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high complexity laboratories.